Currently investigating and phenotyping auditory characteristics in several rare genetic disorders. These projects are multidisciplinary and involve collaboration with otolaryngology, neurology and geneticists.
Participating in several projects in which heritability of auditory processing skills is being evaluated. One study involves an annual trip to a Twins Festival in which data is gathered on monozygotic and dizygotic twins to evaluate heritability. Another study is investigating auditory function in a group of subjects with tune deafness. Measures of interest include otoacoustic emissions and pitch perception.
Pryor, S. P ., Demmler, G. J ., Madeo, A. C ., Yang, Y ., Zalewski, C. K ., Brewer, C. C ., Butman, J. A ., Fowler, K. B ., Griffith, A. J . (2005). Investigation of the role of congenital cytomegalovirus infection in the etiology of enlarged vestibular aqueducts. Archives of Otolaryngology Head & Neck Surgery, 131(5), 388-92.
Pryor, S. R., Madeo, A. C., Reynolds, J. C., Sarlis, A. J., Arnos, K. S., Nance, W. E., Yang, Y., Zalewski, C. K., Brewer, C. C., Butman, J. A., Griffith, A. J. (2005). SLC26A4/PDS genotype-phenotypr correlation in hearing loss with enlargement of the vestibular aqueduct (EVA): evidence that Pendred Syndrome and non-sydromic EVA are distinct clinical and genetic entities. Journal of Medical Genetics, 42: 159-165.
Zalewski, C., Park, G., Kim, Hung, J.; Braun, A.; Rudy, S., Brewer, C. (2005). TTS following MRI in a patient with absent acoustic reflexes. Poster presented at: American Academy of Audiology Convention , March 30- April 2, 2005 .
Brewer, C., Zalewski, C., Kim, J., Segar, A., King, K., Goldbach-Mansky, R. (2005). Auditory phenotype of neonatal onset multisystem inflammatory disease. Poster presented at: American Academy of Audiology Convention , March 30- April 2, 2005 .
Brewer, C., Morell, R., Zalewski, C., Drayna, D., and Friedman, T. (2005). An estimate of heritability of auditory processing skills. Poster presented at: American Academy of Audiology Convention , March 30- April 2, 2005 .
Morrell, R., Brewer, C., Zalewski, C., Mastrioanni, M., Drayna, D., Laws, K., Segar, A. & Friedman, T. (2004). An estimate of heritability of auditory processing skills [Abstract]. Association for Research in Otolaryngology, Midwinter Research Meeting, 141.
Brewer, C., Zalewski, C., Solomon, B., McCullagh, L. & Smith, A. (2003). Audiologic findings in patients with Smith-Magenis syndrome. Poster session presented at the American Speech-Language-Hearing Association Annual Convention, Chicago.
